Donovanosis is a sexually transmitted infection (STI) caused by the bacterium Klebsiella granulomatis. It is characterized by the presence of painless ulcerative lesions on the genitalia, and, less commonly, on other areas such as the mouth or skin. These lesions can progressively increase in size and may lead to complications if left untreated.

The infection is transmitted through sexual contact with an infected individual, and it is more commonly reported in tropical and subtropical regions, particularly in parts of Africa, India, and Papua New Guinea. Diagnosis is typically made through clinical examination and laboratory testing, including the identification of the causative bacterium in tissue samples.

Treatment usually involves the administration of antibiotics, with azithromycin or doxycycline being commonly prescribed. Early intervention is crucial to prevent potential complications, such as secondary infections or scarring.

Preventive measures include safe sex practices, such as the use of condoms, and regular STI screenings for sexually active individuals, especially those in high-risk populations.